Bioss Inc.'s 4E-BP1/2/3 (Thr45) (3G2) Monoclonal Antibody is a Mouse monoclonal antibody. The 4E-BP1/2/3 (Thr45) (3G2) Monoclonal Antibody was generated using ABCA1 as the antigen. It reacts with Human, and Rat. This antibody has been shown to work in applications such as: Western Blot.
Description
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. In humans, this protein functions as a cholesterol efflux pump in the cellular lipid removal pathway. Mutations in the human gene have been associated with Tangier's disease and familial high-density lipoprotein deficiency